Ursolic Acid - an overview | ScienceDirect Topics
#UrsolicAcid Ursolic acid is a lipophilic pentacyclic triterpenoid, especially abundant in apple peel, with anti-inflammatory and antihyperlipidemic properties . Recently, ursolic acid has been identified as a possible remedy for muscle atrophy in a screen for small-molecule inhibitors of skeletal muscle wasting in mice . Interestingly, supplementation with ursolic acid to mice on a high-fat diet increased muscle mass and strength, improved glucose tolerance, promoted brown adipose tissue deposition, and decreased white adipose tissue mass and the severity of hepatic steatosis . These findings suggest that ursolic acid might represent an effective nutritional aid to counteract age-related changes in body composition and metabolic derangements. However, the effect of supplementation with ursolic acid in older adults with sarcopenia has yet to be investigated.
&neo 2020-01-21 23:32:16